Kelly® Science & Clinical is seeking to connect with PhD-level Immunologists for future opportunities with our clients in the San Francisco Bay Area. If you’re passionate about bringing the latest scientific discoveries to life and are ready to take the next step in your career, trust The Experts at Hiring Experts.
Workplace: Onsite in the Bay Area
Pay rate: $100,000-140,000/year
Responsibilities

• Independently conceive, design, and execute in vitro immunological assays using primary immune cells and tumor co-culture systems, including cytokine profiling, cytotoxicity, and flow cytometry-based functional assays.
  

• Design and implement in vivo studies (both internal and external), including murine tumor xenograft modeling and pharmacokinetic analyses for large molecules.
  

• Effectively manage collaborations with third-party vendors (vivariums, CROs, etc.) and internal cross-functional teams to ensure timely and successful execution of research studies.
  

• Support early-stage target discovery and validation by generating TCR-transgenic cell lines, screening putative peptide/HLA targets, and reviewing relevant target biology for program nomination.
  

• Collaborate on multidisciplinary project teams, working closely with colleagues in protein sciences and program management to progress candidate therapeutics through various stages of development.
  

• Maintain awareness of advancements in the T cell engager field and proactively incorporate innovative methodologies and industry best practices.

Qualifications.

• PhD with 4-6 years of relevant experience, or Master’s degree with 8-10 years; title and compensation dependent on qualifications.
  

• Demonstrated expertise in immunology and in vitro assessment of primary immune cell function, including proficiency with MSD/ELISA, Incucyte or similar platforms, flow cytometry, FACS, and other functional plate reader assays (e.g., LDH release).
  

• Hands-on experience working with murine tumor models.
  

• Previous experience in drug discovery and development environments, with strong organizational skills supporting multiple concurrent projects and cross-functional collaborations.
  

• Rigorous and detailed recordkeeping, including electronic lab notebooks, experiment documentation, and compliance with regulatory standards.

Preferred:

• Expertise in therapeutic efficacy studies using humanized mouse and tumor xenograft models.
  

• Experience in the discovery and/or development of bispecific T cell engagers.
  

• In-depth knowledge of TCR/pMHC interactions and antigen processing pathways.
  

• Bioanalytical or regulatory experience supporting IND or similar filings.
  

• Familiarity with project tracking and management tools such as Benchling.

What happens next?
Once you apply, you’ll proceed to the next steps if your skills and experience look like a good fit. But don’t worry – even if this position doesn’t work out, you’re still in our network. That means our team of expert Science & Clinical recruiters will have access to your profile, making your opportunities limitless.
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